Depressed patients have more frequent chest pain even in the absence of coronary artery disease, according to results from the Emory Cardiovascular Biobank presented at ESC Congress today by Dr Salim Hayek, a cardiologist at Emory University School of Medicine in Atlanta, Georgia, US. The findings suggest that pain and depression may share a common neurochemical pathway.
“Depression is a common and well recognised risk factor for the development of heart disease,” said Dr Hayek. “Patients with known heart disease and depression tend to experience chest pain more frequently. However until now, it was not known whether that association was dependent on underlying coronary artery disease.”
The current study assessed whether depression was associated with chest pain independently of underlying coronary artery disease. The study included 5 825 adults enrolled in the Emory Cardiovascular Biobank between 2004 and 2013. The biobank is a prospective registry of patients undergoing cardiac catheterization at three Emory Healthcare sites in Atlanta.