Studies Support Use of Team-Based Care for Early Psychosis

Researchers continue to build on findings from NIMH’s Recovery After an Initial Schizophrenia Episode (RAISE) program, which investigated the effectiveness of early intervention services for people experiencing first episode psychosis. Two recent studies add to the evidence that team-based early intervention services are feasible in real-world health care settings and result in improved outcomes for patients.

Christoph Correll, M.D., of the Center for Psychiatric Neuroscience at the Feinstein Institute for Medical Research in Manhasset, NY, led a team of researchers from eight countries conducting a meta-analysis of studies of early intervention services for psychosis. The meta-analysis combined data from ten randomized clinical trials, including the RAISE Early Treatment Program and the Specialized Treatment for Early Psychosis (STEP) Program. The early intervention services in every study had to be aimed specifically at early psychosis and comprise different elements of treatment (psychosocial and pharmacologic) and supportive services, such as for employment and education. In each study, a control group received treatment as usual for comparison. The combined trials included 2,176 participants with studies lasting from 6 to 24 months.

Full story at NIMH

Team-based Care Optimizes Medication Treatment for First Episode Psychosis

Team-based coordinated specialty care (CSC) for first episode psychosis (FEP) resulted in more optimal prescribing of antipsychotics and fewer side effects when compared with typical community care, according to findings from NIMH’s Recovery After an Initial Schizophrenia Episode (RAISE) project. These findings add detail about this component of treatment to findings from the original RAISE Early Treatment Program (RAISE-ETP) study, which found improved treatment outcomes with CSC versus typical care.

Psychosis is used to describe conditions that affect the mind, where there has been some loss of contact with reality. Symptoms of psychosis include delusions (false beliefs) and hallucinations (seeing or hearing things that others do not see or hear). Untreated, psychotic symptoms can lead to disruptions in school and work, strained family relations, and separation from friends. In a series of reports, the RAISE project has provided information on the feasibility and benefits of individualized, timely care for young people with early psychosis.

Full story at NIMH