Researchers continue to build on findings from NIMH’s Recovery After an Initial Schizophrenia Episode (RAISE) program, which investigated the effectiveness of early intervention services for people experiencing first episode psychosis. Two recent studies add to the evidence that team-based early intervention services are feasible in real-world health care settings and result in improved outcomes for patients.
Christoph Correll, M.D., of the Center for Psychiatric Neuroscience at the Feinstein Institute for Medical Research in Manhasset, NY, led a team of researchers from eight countries conducting a meta-analysis of studies of early intervention services for psychosis. The meta-analysis combined data from ten randomized clinical trials, including the RAISE Early Treatment Program and the Specialized Treatment for Early Psychosis (STEP) Program. The early intervention services in every study had to be aimed specifically at early psychosis and comprise different elements of treatment (psychosocial and pharmacologic) and supportive services, such as for employment and education. In each study, a control group received treatment as usual for comparison. The combined trials included 2,176 participants with studies lasting from 6 to 24 months.