cocaine

A single cocaine dose lowers perceptions of sadness and anger

A single dose of cocaine can interfere with the ability to recognise negative emotions, according to new research presented at the ECNP conference in Amsterdam. In a placebo-controlled within subject study, researchers from the Netherlands and Germany took 24 students (aged 19 to 27) with light to moderate cocaine use, and gave them either 300mg of oral cocaine, or a placebo. After 1 to 2 hours, each participant was then subject to a series of…

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Cocaine changes brain, makes relapse more common in addicts

Cocaine use causes ‘profound changes’ in the brain that lead to an increased risk of relapse due to stress — according to new research from the University of East Anglia. New research published in The Journal of Neuroscience identifies a molecular mechanism in the reward centre of the brain that influences how recovering cocaine addicts might relapse after stressful events. Importantly, the study identifies a potential mechanism for protecting against such relapses with treatment. The research team…

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