PsychENCODE Consortium

2,000 Human Brains Yield Clues to How Genes Raise Risk for Mental Illnesses

It’s one thing to detect sites in the genome associated with mental disorders; it’s quite another to discover the biological mechanisms by which these changes in DNA work in the human brain to boost risk. In their first concerted effort to tackle the latter, 15 collaborating research teams of the National Institutes of Health- (NIH-) funded PsychENCODE Consortium leveraged statistical power gained from a large sample of about 2000 postmortem human brains. The teams published their findings…

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