seizure severity

Neurons’ response to seizure-induced stress reduces seizure severity

In response to seizures, the endoplasmic reticulum (ER), a network of flattened tubes in the cell that packages and transports proteins, triggers a stress response that reduces brain activity and seizure severity. The new findings, reported by Nien-Pei Tsai and colleagues at University of Illinois at Urbana-Champaign on 26th September in PLOS Genetics, may have important implications for the development of new epilepsy therapies. For one-third of epilepsy patients, existing anti-epileptic drugs don’t effectively prevent the…

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